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Endocrine Abstracts

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ea0049ep76 | Adrenal cortex (to include Cushing's) | ECE2017

Clinical course of patients with adrenal incidentaloma: retrospective analysis of a single center

Serrano Ana Carolina Ruiz , Colet Ana Megia , Cortes Silvia Naf , Ortega Joan Vendrell , Muela Inmaculada Simon , Fraile Esther Solano , Alevras Theodora Michalopoulou

In the adrenal incidentaloma (AI) it is fundamental to determine functionality and benignity. The aim of this study was to evaluated the clinical, radiological and hormonal evolution of AI and compare the frequency of autonomous cortisol secretion (ACS) between American and European Guidelines.Methods: Retrospective evaluation of patients with AI referred to our service in the last 5 years.Results: 140 patients were included, 50.9%...
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ea0090ep730 | Pituitary and Neuroendocrinology | ECE2023

Precision medicine in acromegaly: results of the ACROFAST study

Puig-Domingo Manel , Marques-Pamies Montserrat , Gil Joan , Valassi Elena , Gimenez-Palop Olga , Hernandez Marta , Taibo Rocio Villar , Biagetti Betina , Villarroya Gemma Xifra , Simo-Servat Andreu , Zavala Roxana , Simon Inmaculada , Araujo-Castro Marta , Centeno Rogelio Garcia , Calatayud Maria , Miguel Federico Vazquez San , Vilarrasa N , Vert Isabel Salinas , Mora Mireia , Hanzu Felicia Alexandra , Novoa Maria Paz De Miguel , Pavon Isabel , Blanco Concepcion , Alvarez-Escola Cristina , Sampedro-Nunez Miguel Antonio , Jorda Mireia , Bernabeu Ignacio , Webb Susan , Marazuela Monica

Medical treatment of acromegaly is currently performed through a trial-error manner using somatostatin receptor ligands (SRLs) as first-line drugs. Average SRLs response is seen in 50% of cases; subsequent drugs are indicated following clinical judgement. Some biomarkers either before or after surgical failure have been reported to predict SRLs response, including intensity in T2 weighted MRI, short acute octreotide test (sAOT), and different molecules such as SST2 and E-cadhe...
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ea0090p411 | Pituitary and Neuroendocrinology | ECE2023

Usefulness of the short version of the acute octreotide test for prediction of first-generation somatostatin receptor ligands response in acromegaly: a validation study with the ACROFAST cohort

Marques-Pamies Montserrat , Gil Joan , Jorda Mireia , Valassi Elena , Biagetti Betina , Hernandez Marta , Gimenez-Palop Olga , Martinez Silvia , Carrato Cristina , Villar Taibo Rocio , Araujo-Castro Marta , Blanco Concepcion , Simon Inmaculada , Simo-Servat Andreu , Xifra Villarroya Gemma , Vazquez San Miguel Federico , Pavon Isabel , Garcia Centeno Rogelio , Zavala Roxana , Alexandra Hanzu Felicia , Mora Mireia , Aulinas Maso Ana , Vilarrasa N , Soledad Librizzi Maria , Paz De Miguel Novoa Maria , Alvarez-Escola Cristina , Pico-Alfonso Antonio , Antonio Sampedro-Nunez Miguel , Salinas Vert Isabel , Fajardo-Montanana Carmen , Camara-Gomez Rosa , Bernabeu Ignacio , Webb Susan , Marazuela Monica , Puig-Domingo Manel

We previously described a short version of the acute octreotide test (sAOT) for predicting somatostatin receptor ligands (SRLs) response in patients with acromegaly1. In the present work, we prospectively reassess the sAOT ability to identify SRLs response in patients from the ACROFAST study using the current GH standards and control criteria and we also correlate sAOT values with E-cadherin tumor expression. Methods: Patients from the ACROFAS...
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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